オリゴペプチドのNMR測定(物質生命化学科)

Abstract

The oligopeptide was synthesized with the peptide bond of Gly in each amino acid (Leu, Phe). By the place where Gly combined, the effect which the hydrogen on α carbon of the amino acid receives was examined The result showed that the chemical shift value changed most, when it made with the amino group of amino acid pepfid bond. Carboxyl group (electron-withdrawing substituent) of amino acid draws resistant the electron near, when there is no concerning the combination. Therefore, the chemical shift value of the hydrogen on α carbon of amino acid greatly changed.